Abstract
Jaundice is a natural phenomenon that recurs constantly and then gradually disappears. A large percentage of newborns suffer from yellowing of the skin and eyes, which is called neonatal jaundice. This research study was conducted in the laboratory department of Tikrit Teaching Hospital in Salah al-Din Governorate, as well as in some private laboratories affiliated with Tikrit city, from March 15, 2025, to September 15, 2025. The study groups included (60) samples of children aged between (1-7) days and were distributed into two groups. The first group included 30 blood samples from healthy children, and 30 blood samples from children with jaundice after confirming that they had a bilirubin level of (15.5-30) mg/dl after conducting tests for the disease and referring them to the doctor. Then, blood was taken from both groups, and separated by centrifugation, and then the biochemical parameters were estimated, which included (bilirubin, C-reactive protein-CRP, glucose, Cholecystokinin-CCK, Potassium-K, Calcium-Ca, Glutathione-GSH, Malondialdehyde-MDA). The results of the present study showed that significant changes occurred in each of the studied variables in the blood serum of children with jaundice compared to the healthy subjects, at a P ≤ 0.05.
Keywords: cholecystokinin , biochemical , neonatal jaundice.
