Abstract
Samples for the current research were collected from women with cancer in the second stage of infection with breast cancer who were taking two doses of chemotherapy in Kirkuk Governorate for the period from (January to the end of February) of the year 2024. 80 blood samples, whose ages ranged between (25-45) years, were collected from clinic visits. . External samples were divided into two groups:
• Patients group: It included (50) samples of blood from women with breast cancer with treatment 2 doses of chemotherapy.
• Control group: It included (30) blood samples from healthy women.
Then, blood was collected from a group of patients and healthy women and was separated by a centrifuge. Then the studied variables were measured, which included (cancer antigen- CA15-3 , interleukin-10- IL-10 , CXCL12, calcium, zinc, iron, estrogen, progesterone, and Xanthine oxidase). Current research results showed a significant elevated in each of the levels (cancer antigen- CA15-3, interleukin-10, CXCL12, calcium, iron, Estrogen, progesterone, and Xanthine oxidase ) also the result showed a significant decrease in progesterone hormone and zinc level in blood serum of patients with B.C simile to the healthy women .
Keywords: Breast cancer, interleukin 10, progesterone and estrogen, mineral