Summary
In this study, substitutes for pyridazine and phthalazine-1,4-dione were prepared by reacting some types of auxins (carboxylic acids), which are important compounds as growth regulators in plants, where they were converted into esters, and then reacted with aqueous hydrazine to obtain acid hydrazide, which in turn reacts with maleic and phthalic anhydrides to reach the target compound. The prepared compounds were identified by simple physical methods such as color and the amount of difference in melting point, and they were also identified by spectroscopic methods by FT-IR and 1H-NMR spectroscopy, and then evaluated their biological activity against bacteria (Pseudomonas aeruginosa) and (Staphylococcus aureus), where a section of them showed a great inhibition, and the other section showed a moderate to somewhat weak effect.

Download Paper